X-linked agammaglobulinemia (XLA): a genetic tyrosine kinase (Btk) disease.

doi:10.1002/bies.950181009

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Article

X-linked agammaglobulinemia (XLA): a genetic tyrosine kinase (Btk) disease.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Oct 1996

Mattsson P T, Vihinen M, Smith C I

Abstract excerpt

X-linked agammaglobulinemia is a heritable immunodeficiency disease caused by a differentiation abnormality, resulting in the virtual absence of B lymphocytes and plasma cells. The affected gene encodes a cytoplasmic protein tyrosine kinase, Bruton's agammaglobulinemia tyrosine kinase, designated...

Topics

Agammaglobulinaemia Tyrosine Kinase
Agammaglobulinemia
Amino Acid Sequence
Animals
Female
Genetic Linkage
Humans
Male
Mice
Models, Molecular
Molecular Sequence Data
Mutation
Protein Conformation
Protein-Tyrosine Kinases
X Chromosome

Source

Open in PubMed

Identifiers

PMID: 8885720
DOI: 10.1002/bies.950181009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8885720-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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