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Article

X-linked agammaglobulinemia (XLA): a genetic tyrosine kinase (Btk) disease.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Oct 1996

Mattsson P T, Vihinen M, Smith C I

Abstract excerpt

X-linked agammaglobulinemia is a heritable immunodeficiency disease caused by a differentiation abnormality, resulting in the virtual absence of B lymphocytes and plasma cells. The affected gene encodes a cytoplasmic protein tyrosine kinase, Bruton's agammaglobulinemia tyrosine kinase, designated Btk. Btk and the other family members, Tec, ltk and Bmx, contain five regions, four of which are common structural and...

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PMID: 8885720
DOI: 10.1002/bies.950181009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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