Article
[V gene repertoire and pathogenic autoantibodies].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 1997
Hirabayashi Y, Munakata Y, Saitou S, Sasaki T
Abstract excerpt
The studies for autoantibody-associated V genes have failed to find any V gene which might be specific for pathogenic autoantibodies in humans; Namely, both normal subjects and patients have immunoglobulin V genes which can encode autoantibodies. Also single V gene can encode antibodies for both foreign antigens and autoantigens. However, some germline V genes such as V3-7 and VH4-21 are preferentially used for...
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