Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunoglobulin genes in autoimmunity.

International archives of allergy and immunology - 1 Jan 1993

Leung P S, Gershwin M E

Abstract excerpt

The contribution of V germline genes and somatic mutation as well as the mechanism governing expression of the various V family genes in response to self-antigens are still unknown. Thus, we are still far from understanding the contribution and role of the B cell repertoire in human autoimmunity. Much of our current data on autoantibody gene repertoire are derived from laboratory generated hybridomas or animal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Autoimmune Diseases
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Immunoglobulin

Share to Immunoglobulin G

Share to Mutation

Source

Identifiers

PMID: 8508048
DOI: 10.1159/000236507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunoglobulin genes in autoimmunity.PMID 8508048Read ↗

Molecular basis of immunoglobulin variable region gene usage in systemic autoimmunitySemantic proximity Read ↗

Immunoglobulin germline gene variation and its impact on human disease.Semantic proximity Read ↗

[Autoantibody genes].Semantic proximity Read ↗

Antibody repertoire analysis in polygenic autoimmune diseasesSemantic proximity Read ↗

B cells in autoimmune diseases: Insights from analyses of immunoglobulin variable (Ig V) gene usageSemantic proximity Read ↗

VH genes of human autoantibodies.Semantic proximity Read ↗

[V gene repertoire and pathogenic autoantibodies].Semantic proximity Read ↗

Molecular characterization of J558 genes encoding tight-skin mouse autoantibodies: identical heavy-chain variable genes code for antibodies with different specificities.Semantic proximity Read ↗

TCR V gene usage in autoimmunity.Semantic proximity Read ↗

The normally expressed kappa immunoglobulin light chain gene repertoire and somatic mutations studied by single-sided specific polymerase chain reaction (PCR); frequent occurrence of features often assigned to autoimmunity.Semantic proximity Read ↗

The genetic basis of autoantibody production.Semantic proximity Read ↗

Human autoimmunity genes in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.