Article
Linkage of a gene causing high bone mass to human chromosome 11 (11q12-13)
American journal of human genetics - 1 Jun 1997
Johnson M L, Gong G, Kimberling W, Reckér S M, Kimmel D B, Recker R B
Abstract excerpt
The purpose of this paper is to report the linkage of a genetic locus (designated "HBM") in the human genome to a phenotype of very high spinal bone density, using a single extended pedigree. We measured spinal bone-mineral density, spinal Z(BMD), and collected blood from 22 members of this kindr...
Topics
- Absorptiometry, Photon
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Bone Density
- Bone Diseases
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Confidence Intervals
- Female
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Male
- Middle Aged
- Osteoporosis