Transcriptionally repressed germ cells lack a subpopulation of phosphorylated RNA polymerase II in early embryos of <i>Caenorhabditis elegans</i> and <i>Drosophila melanogaster</i>

Abstract excerpt

Early embryonic germ cells in C. elegans and D. melanogaster fail to express many messenger RNAs expressed in somatic cells. In contrast, we find that ribosomal RNAs are expressed in both cell types. We show that this deficiency in mRNA production correlates with the absence of a specific phosphoepitope on the carboxy-terminal domain of RNA polymerase II. In both C. elegans and Drosophila embryos, this...

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