Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<i>zif-1</i>translational repression defines a second, mutually exclusive OMA function in germline transcriptional repression

9 Sept 2010

Abstract excerpt

Specification of primordial germ cells requires global repression of transcription. In C. elegans, primordial germ cells are generated through four rounds of asymmetric divisions, starting from the zygote P0, each producing a transcriptionally repressed germline blastomere (P1-P4). Repression in P2-P4 requires PIE-1, which is provided maternally in oocytes and segregated to all germline blastomeres. We have shown...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics, Aging, and Longevity in Model Organisms
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20826530
DOI: 10.1242/dev.055327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<i>zif-1</i>translational repression defines a second, mutually exclusive OMA function in germline transcriptional repressionPMID 20826530Read ↗

The Conserved Kinases CDK-1, GSK-3, KIN-19, and MBK-2 Promote OMA-1 Destruction to Regulate the Oocyte-to-Embryo Transition in C. elegans.Semantic proximity Read ↗

A conserved triple arginine motif in OMA-1 is required for RNA-binding activity and embryo viability.Semantic proximity Read ↗

Cellular remodeling and JAK inhibition promote zygotic gene expression in the <i>Ciona</i> germlineSemantic proximity Read ↗

eIF4E assembly into <i>C. elegans</i> germ granules is essential for its repressive functionSemantic proximity Read ↗

Germline Blastomeres transcriptomics in the presence or absence of PIE-1 during <i>C. elegans</i> early embryogenesisSemantic proximity Read ↗

emb-4 is a conserved gene required for efficient germline-specific chromatin remodeling during Caenorhabditis elegans embryogenesis.Semantic proximity Read ↗

Characterization of factors that underlie transcriptional silencing in <i>C. elegans</i> oocytesSemantic proximity Read ↗

Characterization of factors that underlie transcriptional silencing in C. elegans oocytesSemantic proximity Read ↗

Two germ granule eIF4E isoforms reside in different mRNPs to hand off <i>C elegans</i> mRNAs from translational repression to activationSemantic proximity Read ↗

The condensin II/TOP-2 axis silences transcription during germline specification in <i>C. elegans</i>Semantic proximity Read ↗

Two zinc finger proteins, OMA-1 and OMA-2, are redundantly required for oocyte maturation in C. elegans.Semantic proximity Read ↗

Genetic requirements for PIE-1 localization and inhibition of gene expression in the embryonic germ lineage of Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.