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Article

Functional analysis of the Drosophila embryonic germ cell transcriptome by RNA interference.

PloS one - 1 Jan 2014

Jankovics Ferenc, Henn László, Bujna Ágnes, Vilmos Péter, Spirohn Kerstin, Boutros Michael, Erdélyi Miklós

Abstract excerpt

In Drosophila melanogaster, primordial germ cells are specified at the posterior pole of the very early embryo. This process is regulated by the posterior localized germ plasm that contains a large number of RNAs of maternal origin. Transcription in the primordial germ cells is actively down-regulated until germ cell fate is established. Bulk expression of the zygotic genes commences concomitantly with the...

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PMID: 24896584
DOI: 10.1371/journal.pone.0098579
PMCID: PMC4045815

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