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Article

p53-based therapeutics for head and neck squamous cell carcinoma.

Oral oncology - 1 Aug 2013

Tassone Patrick, Old Matthew, Teknos Theodoros N, Pan Quintin

Abstract excerpt

Inactivation of the tumor suppressor p53 is a pathogenetic event in the development of head and neck squamous cell carcinoma (HNSCC). In the absence of functional wildtype p53, HNSCC cells have increased resistance to standard chemotherapeutics and radiation. Numerous approaches to restore p53 function in cancer cells have been developed over the past several decades. This review article focuses on viral...

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Identifiers

PMID: 23623836
DOI: 10.1016/j.oraloncology.2013.03.447
PMCID: PMC3710521

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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