Article
G/T polymorphism in the interleukin-2 exon 1 region among Han Chinese systemic lupus erythematosus patients in Taiwan.
Clinical immunology (Orlando, Fla.) - 1 Oct 2008
Lin Ying-Ju, Wan Lei, Sheu Jim Jinn-Chyuan, Huang Chung-Ming, Lin Cheng-Wen, Lan Yu-Ching, Lai Chih-Ho, Hung Chien-Hui, Tsai Yuhsin, Tsai Chang-Hai, Lin Wei-Yong, Liu Hsin-Ping, Lin Ting-Hsu, Huang Yu-Min, Tsai Fuu-Jen
Abstract excerpt
Interleukin-2 (IL-2), one of the crucial immunoregulatory cytokines required for T lymphocyte activation, plays an important role in autoimmune diseases. An IL-2 genetic G/T polymorphism (rs2069763) has been linked with multiple sclerosis and rheumatoid arthritis. We tested a hypothesis that this...
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