Article
Systemic lupus erythematosus with nephritis is strongly associated with the TNFB*2 homozygote in the Korean population.
Human immunology - 1 Mar 1996
Kim T G, Kim H Y, Lee S H, Cho C S, Park S H, Choi H B, Han H, Kim D J
Abstract excerpt
To evaluate the association of TNFB NcoI polymorphism with SLE in the Korean population, we investigated the frequencies of the TNFB and HLADRB1 alleles in 281 controls and 97 SLE patients, including 56 patients with nephritis and 41 patients without nephritis. The frequency of the TNFB*2 homozygote in SLE was significantly increased over controls (43.3% vs 28.5%, RR = 1.9,p < 0.01). In SLE with nephritis, the...
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