Article
Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease.
Nature genetics - 1 Oct 1995
Okuizumi K, Onodera O, Namba Y, Ikeda K, Yamamoto T, Seki K, Ueki A, Nanko S, Tanaka H, Takahashi H, Oyanagi K, Mizusawa H, Kanazawa I, Tsuji S
Abstract excerpt
A specific isoform of apolipoprotein E has been associated with the accelerated rate of disease expression of sporadic Alzheimer's disease (AD) and late-onset familial AD (FAD). An earlier age at onset has also been demonstrated in familial AD patients with mutations in the amyloid precursor prot...
Topics
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Base Sequence
- Cerebral Cortex
- Chromosomes, Human, Pair 14
- DNA Primers
- Humans
- Japan
- Molecular Sequence Data
- Odds Ratio
- Polymerase Chain Reaction