Article
Aspirin-induced asthma and HLA-DRB1 and HLA-DPB1 genotypes.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 May 1997
Dekker J W, Nizankowska E, Schmitz-Schumann M, Pile K, Bochenek G, Dyczek A, Cookson W O, Szczeklik A
Abstract excerpt
BACKGROUND: Aspirin-induced asthma (AIA) affects one in 10 individuals with adult-onset asthma. It is not known if aspirin sensitivity is due to immune mechanisms or to interference with biochemical pathways. OBJECTIVE: The study aimed to test for possible involvement of the genes of the Major Hi...
Topics
- Adult
- Aged
- Alleles
- Allergens
- Aspirin
- Asthma
- Bronchial Provocation Tests
- Female
- HLA-DP Antigens
- HLA-DR Antigens
- Humans
- Male
- Middle Aged
- Odds Ratio
- Polymerase Chain Reaction
- Skin Tests
