Article
Genome-wide association study of aspirin-exacerbated respiratory disease in a Korean population.
Human genetics - 1 Mar 2013
Park Byung Lae, Kim Tae-Hoon, Kim Jeong-Hyun, Bae Joon Seol, Pasaje Charisse Flerida A, Cheong Hyun Sub, Kim Lyoung Hyo, Park Jong-Sook, Lee Ho Sung, Kim Myung-Sin, Choi Inseon S, Choi Byoung Whui, Kim Mi-Kyeong, Shin SeungWoo, Shin Hyoung Doo, Park Choon Sik
Abstract excerpt
Aspirin-exacerbated respiratory disease (AERD) is a nonallergic clinical syndrome characterized by a severe decline in forced expiratory volume in one second (FEV1) following the ingestion of non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin. The effects of genetic variants have not fully explained all of the observed individual differences to an aspirin challenge despite previous attempts to...
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