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Article

HLA-DRB and HLA-DQ genetic variability in patients with aspirin-exacerbated respiratory disease.

American journal of rhinology & allergy - 1 Jan 2000

Esmaeilzadeh Hossein, Nabavi Mohammad, Amirzargar Ali Akbar, Aryan Zahra, Arshi Saba, Bemanian Mohammad Hassan, Fallahpour Morteza, Mortazavi Negar, Rezaei Nima

Abstract excerpt

BACKGROUND: Major histocompatibility complex (MHC) class II is involved in T-cell activation, cytokine secretion, and induction of immune responses. Cytokines, staphylococcus super antigens, and eosinophil activation are proposed to play important roles in aspirin-exacerbated respiratory disease (AERD). OBJECTIVES: This study is aimed at investigating the association of HLA-DRB and DQ genetic variabilities in...

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Identifiers

PMID: 25975240
DOI: 10.2500/ajra.2015.29.4154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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