Article
Asthma and HLA system.
Allergie et immunologie - 1 Sept 1991
Perichon B, Krishnamoorthy R
Abstract excerpt
Study of atopic asthma provides an excellent model for our understanding of the complex molecular genetics of human immune responsiveness. Family and population studies have suggested that multiple genetic factors influence global and specific immune responsiveness to allergens. Global response of IgE production appears to be controlled by a dominant "atopy gene" unlinked to HLA class II associated Ir genes,...
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