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Article

Asthma and HLA system.

Allergie et immunologie - 1 Sept 1991

Perichon B, Krishnamoorthy R

Abstract excerpt

Study of atopic asthma provides an excellent model for our understanding of the complex molecular genetics of human immune responsiveness. Family and population studies have suggested that multiple genetic factors influence global and specific immune responsiveness to allergens. Global response of IgE production appears to be controlled by a dominant "atopy gene" unlinked to HLA class II associated Ir genes,...

Topics

Alleles
Aspirin
Asthma
Base Sequence
Disease Susceptibility
Genes, Dominant
Genetic Markers
Genetic Predisposition to Disease
HLA Antigens
Haplotypes
Humans
Hypersensitivity, Immediate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoglobulin A

Immunoglobulin E

Molecular Sequence Data

Phenotype

Polymorphism, Genetic

Source

Identifiers

PMID: 1741930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1741930-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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