Article
The human leucocyte antigen-DRB1*1302-DQB1*0609-DPB1*0201 haplotype may be a strong genetic marker for aspirin-induced urticaria.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Mar 2005
Kim S-H, Choi J-H, Lee K-W, Kim S-H, Shin E-S, Oh H-B, Suh C-H, Nahm D-H, Park H-S
Abstract excerpt
BACKGROUND: Urticaria/angioedema is a common aspirin-induced allergy; however, its pathogenic mechanism is not understood. OBJECTIVE: In order to uncover the genetic mechanism, we studied the associations of the human leucocyte antigen (HLA) genotypes in patients with aspirin-induced urticaria compared with aspirin-intolerant asthma and normal control in a Korean population. METHODS: Ninety-four aspirin-induced...
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