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Article

In vitro transcriptional activation of p21 promoter by p53.

Biochemical and biophysical research communications - 19 May 1997

Kim T K

Abstract excerpt

The tumor suppressor p53 can control cell growth by inducing cell cycle arrest. This is effected, at least in part, by transcriptional activation of p21 gene, a cell cycle inhibitor. Here in vitro transcription assay for p21 has been established. The assay recapitulates activation of p21 promoter mediated by p53 in vitro. Thus this in vitro assay will allow to study how transcriptional regulation of p21 can be...

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Share to Cell Transformation, Neoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9177263
DOI: 10.1006/bbrc.1997.6637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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