Article
Resolution of an early RecA-recombination intermediate by a junction-specific endonuclease.
Proceedings of the National Academy of Sciences of the United States of America - 10 Jun 1997
Chiu S K, Low K B, Yuan A, Radding C M
Abstract excerpt
The nucleoprotein filament formed on a circular single strand by Escherichia coli RecA protein in vitro can pair with homologous duplex DNA even when the latter lacks a free homologous end, but subsequent progression of the reaction through strand exchange requires an end in at least one strand of the duplex DNA. We purified from E. coli an endonuclease activity that cleaves the outgoing strand of duplex DNA at...
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