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Article

The RecU Holliday junction resolvase acts at early stages of homologous recombination.

Nucleic acids research - 1 Sept 2008

Cañas Cristina, Carrasco Begoña, Ayora Silvia, Alonso Juan C

Abstract excerpt

Homologous recombination is essential for DNA repair and generation of genetic diversity in all organisms. It occurs through a series of presynaptic steps where the substrate is presented to the recombinase (RecA in bacteria). Then, the recombinase nucleoprotein filament mediates synapsis by first promoting the formation of a D-loop and later of a Holliday junction (HJ) that is subsequently cleaved by the HJ...

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Identifiers

PMID: 18684995
DOI: 10.1093/nar/gkn500
PMCID: PMC2532717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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