Article
Transcriptional activation of the human growth hormone gene by ras oncogene.
Molecular and cellular endocrinology - 25 Apr 1997
Petersenn S, Maaser C, Schulte H M
Abstract excerpt
ras Oncogenes play an important role in causing cellular transformation and proliferation. They have been implicated in the formation of many human tumors but only rarely been identified in pituitary adenomas. We studied the effect of ras activation on growth hormone (GH) production. Transcriptional regulation of human GH was investigated by transient transfections in a pituitary cell line GH4 using different...
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