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Article

Characterization of Methanobacterium thermoautotrophicum Marburg mutants defective in regulation of L-tryptophan biosynthesis.

Journal of bacteriology - 1 Jun 1997

Gast D A, Wasserfallen A, Pfister P, Ragettli S, Leisinger T

Abstract excerpt

Three nitrosoguanidine-induced mutants of the archaeon Methanobacterium thermoautotrophicum Marburg resistant to 5-methyltryptophan were isolated and characterized. They were found to take up L-tryptophan, as wild-type cells, via an energy-dependent, low-affinity transport system specific for L-tryptophan, with a Km of 300 microM and a Vmax of 7 nmol/mg (dry weight)/min. Resistance to 5-methyltryptophan was not...

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Identifiers

PMID: 9171414
DOI: 10.1128/jb.179.11.3664-3669.1997
PMCID: PMC179162

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Source receipt: pubmed, retrieved 7 Sept 2026.

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