Article
The small-eye mutation results in abnormalities in the lateral cortical migratory stream.
Brain research. Developmental brain research - 10 Sept 1998
Brunjes P C, Fisher M, Grainger R
Abstract excerpt
Mice with homozygous mutations of the Pax-6 gene exhibit a constellation of developmental problems including the absence of eyes and nasal cavities and problems in the movement of neuroblasts out of the germinal epithelium. In this paper, we demonstrate further disturbances in neuronal migration. Normally, cells produced along the lateral ventricles move laterally across the pallium, ultimately coming to reside...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.