Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel role for Pax6 in the segmental organization of the hindbrain.

Development (Cambridge, England) - 1 May 2013

Kayam Galya, Kohl Ayelet, Magen Zohar, Peretz Yuval, Weisinger Karen, Bar Avi, Novikov Orna, Brodski Claude, Sela-Donenfeld Dalit

Abstract excerpt

Complex patterns and networks of genes coordinate rhombomeric identities, hindbrain segmentation and neuronal differentiation and are responsible for later brainstem functions. Pax6 is a highly conserved transcription factor crucial for neuronal development, yet little is known regarding its early roles during hindbrain segmentation. We show that Pax6 expression is highly dynamic in rhombomeres, suggesting an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Mapping
Share to Cycloheximide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Early Growth Response Protein 2

Share to Electroporation

Share to MafB Transcription Factor

Share to Paired Box Transcription Factors

Share to PAX6 Transcription Factor

Share to Rhombencephalon

Source

Identifiers

PMID: 23578930
DOI: 10.1242/dev.089136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel role for Pax6 in the segmental organization of the hindbrain.PMID 23578930Read ↗

Analysis of hindbrain patterning defects caused by the kreisler(enu) mutation reveals multiple roles of Kreisler in hindbrain segmentation.Semantic proximity Read ↗

c-jun regulation and function in the developing hindbrain.Semantic proximity Read ↗

Segmental expression of Hoxa-2 in the hindbrain is directly regulated by Krox-20.Semantic proximity Read ↗

spiel ohne grenzen/pou2 is required for zebrafish hindbrain segmentation.Semantic proximity Read ↗

Krox20 controls the transcription of its various targets in the developing hindbrain according to multiple modes.Semantic proximity Read ↗

Eph signalling functions downstream of Val to regulate cell sorting and boundary formation in the caudal hindbrain.Semantic proximity Read ↗

Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.Semantic proximity Read ↗

Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon.Semantic proximity Read ↗

Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon.Semantic proximity Read ↗

Krox20 hindbrain regulation incorporates multiple modes of cooperation between cis-acting elements.Semantic proximity Read ↗

Hoxb-2 transcriptional activation in rhombomeres 3 and 5 requires an evolutionarily conserved cis-acting element in addition to the Krox-20 binding site.Semantic proximity Read ↗

Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.