Article
The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain.
Development (Cambridge, England) - 1 Jun 1997
Macdonald R, Scholes J, Strähle U, Brennan C, Holder N, Brand M, Wilson S W
Abstract excerpt
No-isthmus (Noi) is a member of the zebrafish Pax family of transcriptional regulators that is expressed in restricted domains of the developing CNS. In the developing eye and optic nerve, the Noi+ cells are primitive glial cells that line the choroid fissure and optic stalk/nerve to its junction...
Topics
- Animals
- Astrocytes
- Axons
- Cell Differentiation
- Choroid
- Coloboma
- DNA-Binding Proteins
- Diencephalon
- Embryo, Nonmammalian
- Embryonic Induction
- Eye
- Ganglia
- Gene Expression Regulation, Developmental
- Hedgehog Proteins
- Homozygote
- Mutation
- Nerve Growth Factors
- Netrin-1