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Article

Temperature-sensitive mutants of Actinobacillus pleuropneumoniae induce protection in mice.

Infection and immunity - 1 Jun 1997

Byrd W, Hooke A M

Abstract excerpt

Temperature-sensitive mutants of Actinobacillus pleuropneumoniae 4074, serotype 1, were isolated after treatment with nitrosoguanidine and enrichment with penicillin and D-cycloserine. Of the four temperature-sensitive mutants evaluated in mice, one (A-1) had a tight phenotype (i.e., it ceased replication immediately after transfer to the nonpermissive temperature [37 degrees C]) and three (1-2, 4-1, and 12-1)...

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Identifiers

PMID: 9169752
DOI: 10.1128/iai.65.6.2206-2210.1997
PMCID: PMC175304

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CAMP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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