Biological evaluation of Mycoplasma pulmonis temperature-sensitive mutants for use as possible rodent vaccines.

doi:10.1128/iai.58.7.2289-2296.1990

Back to search

Article

Biological evaluation of Mycoplasma pulmonis temperature-sensitive mutants for use as possible rodent vaccines.

Infection and immunity - 1 Jul 1990

Lai W C, Bennett M, Lu Y S, Pakes S P

Abstract excerpt

Temperature-sensitive mutants (TSMs) of Mycoplasma pulmonis were produced by treating the wild-type strain with N-methyl-N'-nitro-N-nitrosoguanidine. Three TSMs were selected at 38 degrees C, as a restrictive temperature, and at 34 degrees C, as a permissive temperature. Two TSMs, UTCMI and UTCMI...

Topics

Animals
Antibodies, Bacterial
Bacterial Vaccines
Female
Lung
Male
Mutation
Mycoplasma
Mycoplasma Infections
Nasal Cavity
Rats
Rats, Inbred Lew
Rodent Diseases
Temperature
Vaccines, Attenuated

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.