Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization and immunogenicity of an apxIA mutant of Actinobacillus pleuropneumoniae.

Veterinary microbiology - 20 Dec 2006

Xu Fuzhou, Chen Xiaoling, Shi Aihua, Yang Bing, Wang Jinluo, Li Yongqing, Guo Xin, Blackall P J, Yang Hanchun

Abstract excerpt

Actinobacillus pleuropneumoniae is the aetiological agent of porcine pleuropneumonia, a highly contagious and often fatal disease. A candidate live vaccine strain, potentially capable of cross-serovar protection, was constructed by deleting the section of the apxIA gene coding for the C-terminal segment of ApxI toxin of the A. pleuropneumoniae serovar 10 reference strain (D13039) and inserting a chloramphenicol...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actinobacillus Infections
Share to Actinobacillus pleuropneumoniae

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bacterial Vaccines

Share to Biological Assay

Share to Hemolysin Proteins

Share to Neutralization Tests

Share to Random Allocation

Share to Vaccines, Attenuated

Source

Identifiers

PMID: 16930871
DOI: 10.1016/j.vetmic.2006.07.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization and immunogenicity of an apxIA mutant of Actinobacillus pleuropneumoniae.PMID 16930871Read ↗

Potential use an Actinobacillus pleuropneumoniae double mutant strain DeltaapxIICDeltaapxIVA as live vaccine that allows serological differentiation between vaccinated and infected animals.Semantic proximity Read ↗

Construction and immunogenicity of a ∆apxIC/ompP2 mutant of Actinobacillus pleuropneumoniae and Haemophilus parasuis.Semantic proximity Read ↗

Construction and immunogencity of a DeltaapxIC/DeltaapxIIC double mutant of Actinobacillus pleuropneumoniae serovar 1.Semantic proximity Read ↗

New trends in innovative vaccine development against Actinobacillus pleuropneumoniae.Semantic proximity Read ↗

Construction and characterization of a live, attenuated apxIICA inactivation mutant of Actinobacillus pleuropneumoniae lacking a drug resistance marker.Semantic proximity Read ↗

Use of an Actinobacillus pleuropneumoniae multiple mutant as a vaccine that allows differentiation of vaccinated and infected animals.Semantic proximity Read ↗

Development of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae infection.Semantic proximity Read ↗

A new variant of Actinobacillus pleuropneumoniae serotype 3 lacking the entire apxII operon.Semantic proximity Read ↗

Comparative genome analyses to understand the population biology and virulence of the pig pathogen Actinobacillus pleuropneumoniaeSemantic proximity Read ↗

Characterization of apxlVA, a new RTX determinant of Actinobacillus pleuropneumoniaeSemantic proximity Read ↗

Knockout mutants of Actinobacillus pleuropneumoniae serotype 1 that are devoid of RTX toxins do not activate or kill porcine neutrophils.Semantic proximity Read ↗

Mutation in the LPS outer core biosynthesis gene, galU, affects LPS interaction with the RTX toxins ApxI and ApxII and cytolytic activity of Actinobacillus pleuropneumoniae serotype 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.