Article
A mutation in cytochrome oxidase subunit 2 restores respiration of the mutant pet ts1402.
Current genetics - 1 May 1997
Meyer W, Bauer M, Pratje E
Abstract excerpt
The yeast PET1402/OXA1 gene encoding a 44.8-kDa protein is required for mitochondrial biogenesis. Substitution of Leu240 to serine in the protein results in an accumulation of the precursor form of the mitochondrially encoded subunit 2 of cytochrome oxidase (Cox2) and temperature-sensitive respir...
Topics
- Amino Acid Sequence
- Cell Respiration
- Chromosome Mapping
- Electron Transport Complex IV
- Genes, Fungal
- Intracellular Membranes
- Molecular Sequence Data
- Peptide Fragments
- Phenotype
- Point Mutation
- Saccharomyces cerevisiae
- Sequence Homology, Amino Acid