Article
Heat shock protein HSP60 can alleviate the phenotype of mitochondrial RNA-deficient temperature-sensitive mna2 pet mutants.
Molecular & general genetics : MGG - 6 Jan 1995
Sanyal A, Harington A, Herbert C J, Groudinsky O, Slonimski P P, Tung B, Getz G S
Abstract excerpt
mna2, which belongs to the class I temperature-sensitive pet mutants that lose mitochondrial (mt)RNA at restrictive temperature, was shown by complementation and sequence determination to correspond to the gene coding for HSP60. Both mna2-1 and mna2-2, the two available alleles of mna2, have cons...
Topics
- Alanine
- Alleles
- Base Sequence
- Blotting, Northern
- Chaperonin 60
- DNA Mutational Analysis
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
- Isoleucine
- Mitochondria
- Molecular Sequence Data
- Oxygen Consumption
- Point Mutation
- RNA
- RNA, Fungal
- RNA, Mitochondrial