Article
A single mutation in the first transmembrane domain of yeast COX2 enables its allotopic expression.
Proceedings of the National Academy of Sciences of the United States of America - 16 Mar 2010
Supekova Lubica, Supek Frantisek, Greer John E, Schultz Peter G
Abstract excerpt
During the course of evolution, a massive reduction of the mitochondrial genome content occurred that was associated with transfer of a large number of genes to the nucleus. To further characterize factors that control the mitochondrial gene transfer/retention process, we have investigated the barriers to transfer of yeast COX2, a mitochondrial gene coding for a subunit of cytochrome c oxidase complex....
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