Characterization of an HIV-1 p24gag epitope recognized by a CD8+ cytotoxic T-cell clone.

doi:10.1016/s0165-2478(97)02696-5

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Article

Characterization of an HIV-1 p24gag epitope recognized by a CD8+ cytotoxic T-cell clone.

Immunology letters - 1 Mar 1997

Buseyne F, Stevanovic S, Rammensee H G, Rivière Y

Abstract excerpt

A CD8+ cytotoxic T-cell clone that recognized HIV p24gag was isolated from an infected individual. The minimal epitope was localized to amino acids 308-316 (QASQEVKNW). Using allogeneic target cells, we found that lysis was restricted by the HLA-Cw0401 molecule. We observed that C1R cells, that e...

Topics

Alleles
CD8-Positive T-Lymphocytes
Cells, Cultured
Clone Cells
Epitope Mapping
Epitopes
HIV Core Protein p24
HIV-1
Histocompatibility Antigens Class I
Humans
Major Histocompatibility Complex
Oligopeptides
T-Lymphocytes, Cytotoxic

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