Article
The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae.
RNA (New York, N.Y.) - 1 Jun 2005
Torchet Claire, Badis Gwenaël, Devaux Frédéric, Costanzo Ginny, Werner Michel, Jacquier Alain
Abstract excerpt
Conversion of uridines into pseudouridines (Psis) is the most frequent base modification in ribosomal RNAs (rRNAs). In eukaryotes, the pseudouridylation sites are specified by base-pairing with specific target sequences within H/ACA small nucleolar RNAs (snoRNAs). The yeast rRNAs harbor 44 Psis, but, when this work began, 15 Psis had completely unknown guide snoRNAs. This suggested that many snoRNAs remained to...
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