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Identification of DNA gyrase A mutations in ciprofloxacin-resistant isolates of Salmonella typhimurium from men and cattle in Germany.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 1995

Heisig P, Kratz B, Halle E, Gräser Y, Altwegg M, Rabsch W, Faber J P

Abstract excerpt

Six multiply resistant isolates of Salmonella typhimurium var. copenhagen with high-level resistance to fluoroquinolones (e.g., MIC of ciprofloxacin: 32 micrograms/ml) were isolated from human patients (n = 3) and from cattle (n = 3). The isolates were examined by complementation tests using a set of broad-host-range plasmids, which carry either the gyrA+ or the gyrB+ genes or a combination of both from...

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PMID: 9158777
DOI: 10.1089/mdr.1995.1.211

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