Article
Colorectal carcinoma. DNA ploidy pattern and prognosis with reference to tumor DNA heterogeneity.
Analytical and quantitative cytology and histology - 1 Oct 1992
Koha M, Wikström B, Brismar B
Abstract excerpt
Nuclear DNA content was measured in 72 colorectal carcinomas using single-cell microspectrophotometry on Feulgen-stained smears. Four samples were analyzed from each tumor. Patients were followed for 41-65 months (average, 53). DNA heterogeneity (both aneuploid and nonaneuploid patterns) was present in 44% of the cases. Sixty-eight percent of the tumors showed an aneuploid DNA pattern in at least one of the...
Topics
- Adult
- Aged
- Aged, 80 and over
- Carcinoma
- Colorectal Neoplasms
- DNA, Neoplasm
- Female
- Genetic Variation
- Humans
- Image Processing, Computer-Assisted
- Male
- Middle Aged