Comparative molecular pathology of sporadic hyperplastic polyps and neoplastic lesions from the same individual.

doi:10.1136/jcp.2004.018507

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Article

Comparative molecular pathology of sporadic hyperplastic polyps and neoplastic lesions from the same individual.

Journal of clinical pathology - 1 Oct 2004

Zauber P, Sabbath-Solitare M, Marotta S, Zauber A, Bishop T

Abstract excerpt

AIM: The biology of colorectal hyperplastic polyps is of considerable relevance, because recent evidence suggests that under certain circumstances hyperplastic polyps may be precursors of neoplasms. The aim of this study was to assess and compare the clinical and molecular characteristics of hyperplastic polyps and neoplastic lesions removed from patients without the hyperplastic polyposis syndrome. METHODS: One...

Topics

Adenoma
Aged
Carcinoma
Colon
Colonic Neoplasms
Colonic Polyps
Colonoscopy
Female
Genes, APC
Genes, ras
Humans
Hyperplasia
Loss of Heterozygosity
Male
Microsatellite Repeats
Middle Aged
Mutation
Polymerase Chain Reaction

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Identifiers

PMID: 15452165
DOI: 10.1136/jcp.2004.018507
PMCID: PMC1770451

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