Article
A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22.
Proceedings of the National Academy of Sciences of the United States of America - 16 Jan 2001
Kelsoe J R, Spence M A, Loetscher E, Foguet M, Sadovnick A D, Remick R A, Flodman P, Khristich J, Mroczkowski-Parker Z, Brown J L, Masser D, Ungerleider S, Rapaport M H, Wishart W L, Luebbert H
Abstract excerpt
Bipolar disorder or manic depressive illness is a major psychiatric disorder that is characterized by fluctuation between two abnormal mood states. Mania is accompanied by symptoms of euphoria, irritability, or excitation, whereas depression is associated with low mood and decreased motivation and energy. The etiology is currently unknown; however, numerous family, twin, and adoption studies have argued for a...
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