Article
Studies of the potential role of the dopamine D1 receptor gene in addictive behaviors.
Molecular psychiatry - 1 Jan 1997
Comings D E, Gade R, Wu S, Chiu C, Dietz G, Muhleman D, Saucier G, Ferry L, Rosenthal R J, Lesieur H R, Rugle L J, MacMurray P
Abstract excerpt
Abnormalities in the dopaminergic reward pathways have frequently been implicated in substance abuse and addictive behaviors. Recent studies by Self and coworkers have suggested an important interaction between the dopamine D1 and D2 receptors in cocaine abuse. To test the hypothesis that the DRD1 gene might play a role in addictive behaviors we examined the alleles of the Dde I polymorphism in three independent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.