Article
Genetics of dopamine receptors and drug addiction.
Human genetics - 1 Jun 2012
Gorwood Philip, Le Strat Yann, Ramoz Nicolas, Dubertret Caroline, Moalic Jean-Marie, Simonneau Michel
Abstract excerpt
Dopamine plays a key role in reward behavior, yet the association of drug dependence as a chronic, relapsing disorder with the genes encoding the various dopaminergic receptor subtypes remains difficult to delineate. In the context of subsequent genome-wide association (GWAS) research and post-GWAS investigations, we summarize the novel data that link genes encoding molecules involved in the dopaminergic system...
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