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Article

Genetics of dopamine receptors and drug addiction: a comprehensive review.

Behavioural pharmacology - 1 Feb 2009

Le Foll Bernard, Gallo Alexandra, Le Strat Yann, Lu Lin, Gorwood Philip

Abstract excerpt

Drug dependence is a chronic, relapsing disorder in which compulsive drug-seeking and drug-taking behaviours persist despite serious negative consequences. Addictive substances, such as opioids, ethanol, psychostimulants and nicotine, induce pleasant states or relieve distress, effects that contribute to their recreational use. Dopamine is critically involved in drug addiction processes. However, the role of the...

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Source

Identifiers

PMID: 19179847
DOI: 10.1097/FBP.0b013e3283242f05

Genes

DRD2
DRD1
DRD3
DRD4
DRD5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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