Article
A subset of senile dementia with high incidence of the apolipoprotein E epsilon2 allele.
Annals of neurology - 1 May 1997
Ikeda K, Akiyama H, Arai T, Sahara N, Mori H, Usami M, Sakata M, Mizutani T, Wakabayashi K, Takahashi H
Abstract excerpt
There is a subset of very elderly patients with senile dementia in whom abundant neurofibrillary tangles are present, mainly in the hippocampal region, without a significant number of senile plaques. In a retrospective neuropathological examination of 239 dementia patients, 14 were found to have this type of senile dementia. The apolipoprotein E epsilon2, epsilon3, and epsilon4 allele frequencies in this patient...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.