Recombination patterns around the breakpoints of a balanced 1;11 autosomal translocation associated with major mental illness.

doi:10.1097/00041444-199624000-00006

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Article

Recombination patterns around the breakpoints of a balanced 1;11 autosomal translocation associated with major mental illness.

Psychiatric genetics - 1 Jan 1996

He L, Carothers A, Blackwood D H, Teague P, Maclean A W, Brown J, Wright A F, Muir W J, Porteous D J, St Clair D M

Abstract excerpt

The frequency and extent of pairing failure around human translocations are unknown. We have examined the pattern of recombination around the breakpoints of a balanced autosomal translocation t(1;11) (q43;q21) associated with major mental illness. DNA was available from 17 carriers and 10 non-tra...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 11
Female
Genetic Carrier Screening
Genetic Linkage
Genetic Markers
Genotype
Haplotypes
Humans
Hybrid Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lod Score

Male

Meiosis

Pedigree

Polymorphism, Genetic

Probability

Psychotic Disorders

Source

Open in PubMed

Identifiers

PMID: 9149326
DOI: 10.1097/00041444-199624000-00006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9149326-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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