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Article

Recombination patterns around the breakpoints of a balanced 1;11 autosomal translocation associated with major mental illness.

Psychiatric genetics - 1 Jan 1996

He L, Carothers A, Blackwood D H, Teague P, Maclean A W, Brown J, Wright A F, Muir W J, Porteous D J, St Clair D M

Abstract excerpt

The frequency and extent of pairing failure around human translocations are unknown. We have examined the pattern of recombination around the breakpoints of a balanced autosomal translocation t(1;11) (q43;q21) associated with major mental illness. DNA was available from 17 carriers and 10 non-translocation carriers with meioses involving four generations. The derivative 1 and 11 chromosomes were also isolated in...

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PMID: 9149326
DOI: 10.1097/00041444-199624000-00006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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