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Article

Centromeric genotyping and direct analysis of nondisjunction in humans: Down syndrome.

Chromosoma - 1 Jun 1998

Shen J J, Sherman S L, Hassold T J

Abstract excerpt

In species with chiasmate meioses, alterations in genetic recombination are an important correlate of nondisjunction. In general, these alterations fall into one of two categories: either homologous chromosomes fail to pair and/or recombine at meiosis I, or they are united by chiasmata that are suboptimally positioned. Recent studies of human nondisjunction suggest that these relationships apply to our species as...

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PMID: 9639654
DOI: 10.1007/s004120050293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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