Article
H2-M3, a full-service class Ib histocompatibility antigen.
Annual review of immunology - 1 Jan 1997
Lindahl K F, Byers D E, Dabhi V M, Hovik R, Jones E P, Smith G P, Wang C R, Xiao H, Yoshino M
Abstract excerpt
H2-M3 is an MHC class Ib molecule of the mouse with a unique preference for N-formylated peptides, which may come from the N-termini of endogenous, mitochondrial proteins or foreign, bacterial proteins. The crystal structure of M3 revealed a hydrophobic peptide-binding groove with an occluded A pocket and the peptide shifted one residue relative to class Ia structures. The formyl group is held by a novel hydrogen...
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