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Article

A polymorphism of the 5 alpha-reductase gene and its association with prostate cancer: a case-control analysis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 1997

Kantoff P W, Febbo P G, Giovannucci E, Krithivas K, Dahl D M, Chang G, Hennekens C H, Brown M, Stampfer M J

Abstract excerpt

Prostate cancer (CaP) is the most commonly diagnosed, nondermatological cancer in the United States. The development and progression of CaP is influenced by androgens. 5 alpha-Reductase, type II, converts testosterone to dihydrotestosterone and is critical to the development of the prostate. A TA dinucleotide repeat polymorphism exists in the 3' untranslated region of the 5 alpha-reductase type II gene. 5...

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PMID: 9138662

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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