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Article

Genetic variability of the human SRD5A2 gene: implications for prostate cancer risk.

Cancer research - 15 Sept 1995

Reichardt J K, Makridakis N, Henderson B E, Yu M C, Pike M C, Ross R K

Abstract excerpt

Elevated dihydrotestosterone levels have been suggested to increase the risk of prostate cancer. The human SRD5A2 gene encodes the type II steroid 5 alpha-reductase, which converts testosterone to the more bioactive compound dihydrotestosterone. We have determined the distribution of a dinucleotide repeat in low-risk Asian-Americans, high-risk African-Americans, and intermediate-risk non-Hispanic Whites. We found...

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PMID: 7664265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variability of the human SRD5A2 gene: implications for prostate cancer risk.PMID 7664265Read ↗

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Polymorphic markers in the SRD5A2 gene and prostate cancer risk: a population-based case-control study.Semantic proximity Read ↗

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