Article
Mutation of ras oncogene in gastric adenocarcinoma: association with histological phenotype.
Anticancer research - 1 Jan 2000
Kim T Y, Bang Y J, Kim W S, Kang S H, Lee K U, Choe K J, Kim N K
Abstract excerpt
In order to explore the role of ras oncogene in gastric carcinomas from Korean patients, we examined the frequency of point mutations all three ras oncogenes (Ki-, Ha-, and N-ras). A total of 57 DNA samples were prepared from 3 gastric carcinoma cell lines, 10 malignant ascites, and 44 frozen gastric tumor tissues. Exons 1 and 2 of each ras oncogene were amplified by polymerase chain reaction (PCR), and analyzed...
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