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Article

The human drug metabolizing cytochromes P450.

Journal of pharmacokinetics and biopharmaceutics - 1 Oct 1996

Wrighton S A, VandenBranden M, Ring B J

Abstract excerpt

The superfamily of heme-thiolate proteins known as the cytochromes P450 is responsible for the oxidative metabolism of the majority of drugs. Thus, the phenotypes of individuals with respect to their levels of catalytically active cytochromes P450 determines to a large part the substantial interindividual variation observed in the metabolic clearance of drugs. Over the past 10 years 15 different human cytochromes...

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Identifiers

PMID: 9131485
DOI: 10.1007/BF02353474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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