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Article

In vitro selection of variants of herpes simplex virus type 1 which differ in cytopathic changes.

Microbiology and immunology - 1 Jan 1997

Padilla J, Yamada M, Takahashi Y, Tsukazaki T, Nakamura J, Yoshida M, Uno F, Arao Y, Nii S

Abstract excerpt

To analyze the mechanisms for in vitro emergence of the syncytial variants of herpes simplex virus type 1 (HSV-1), several cell lines were infected with a mixture of equal amounts of two HSV-1 variants, one syncytial and the other non-syncytial, and changes in their relative abundance were monitored during passage. With a combination of two variants of the Miyama strain of HSV-1, the syncytial variant became...

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Identifiers

PMID: 9130231
DOI: 10.1111/j.1348-0421.1997.tb01191.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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