Article
<i>In vitro</i> evolution of herpes simplex virus 1 (HSV-1) reveals selection for syncytia and other minor variants in Vero cell culture
2019-09-06
Abstract excerpt
The large dsDNA virus HSV-1 is often considered to be genetically stable, however it is known to rapidly evolve in response to strong selective pressures such as antiviral drug treatment. Deep sequencing analysis has revealed that clinical and laboratory isolates of this virus exist as populations that contain a mixture of minor alleles or variants, similar to many RNA viruses. Classical virology methods often use...
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Identifiers and source
- Literature Corpus work
- 820847e1-f991-5180-ac48-0b40779d5620
- DOI
- 10.1101/760629