Article
In vitro divergence of HSV-1 populations propagated in different cell lines.
Archives of virology - 1 Jan 1990
Epstein A L, Lyon M, Michal Y, Jacquemont B
Abstract excerpt
To investigate how the structure of a virus population is influenced by the particular cell types in which the virus is propagated, laboratory populations of HSV-1 have been serially passaged onto a number of different cell lines, differing either in species or in tissue specificity. After a limi...
Topics
- Animals
- Cell Line
- DNA Restriction Enzymes
- DNA, Viral
- Glycoproteins
- Humans
- Phenotype
- Selection, Genetic
- Serial Passage
- Simplexvirus
- Viral Proteins