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Article

In vitro divergence of HSV-1 populations propagated in different cell lines.

Archives of virology - 1 Jan 1990

Epstein A L, Lyon M, Michal Y, Jacquemont B

Abstract excerpt

To investigate how the structure of a virus population is influenced by the particular cell types in which the virus is propagated, laboratory populations of HSV-1 have been serially passaged onto a number of different cell lines, differing either in species or in tissue specificity. After a limited number of in vitro passages, several of the daughter virus populations have diverged in the expression of at least...

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Identifiers

PMID: 2158287
DOI: 10.1007/BF01310511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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